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In companion birds the absence of coronary artery disease, the prognosis for complete recovery is excellent. About 2/3 of coronary aneurysms regress within 1 yr, although it is unknown whether residual coronary stenosis remains. Giant coronary aneurysms (> 8 mm internal diameter on companion birds echocardiogram) are less likely to regress and require more intensive follow-up and therapy. Treatment Children with Kawasaki syndrome should be treated by or in close consultation with an experienced companion birds pediatric cardiologist or pediatric infectious disease specialist. Therapy is started as soon as possible, optimally within the first 10 days of illness, with a combination of high-dose immune globulin intravenous (IGIV--a single dose of 2 g/kg given over 10 to 12 h) and oral high-dose aspirin (80 to 100 mg/kg/day in 4 divided doses). The aspirin dose is reduced to 3 to 5 mg/kg/day as a single dose when the child becomes afebrile.
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