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The remaining 322 patients (183 girls, 56.8%) were enrolled into the study. Physical examinations and anthropometric measurements of all the patients were performed. The calculated body mass indexes (BMI: weight/height[2]) of the patients were proportioned to the BMI of age- and sex- matched children in the 50th percentile, then 'liver biopsy' multiplied by 100. The 'liver biopsy' ratio above 120 was accepted as obesity[13]. Hepatomegaly was defined as a liver edge greater than 2 cm below the right costal margin[14]. Biochemical tests of patients were performed after a 12-hour fasting 'liver biopsy' period. The levels of fasting serum glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyl transpeptidase (GGT), total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides were measured. ALT and AST normal limits were 5-45 U/L[15]. Total protein, albumin, total bilirubin and prothrombin time were tested if the patients’ AST and ALT levels were above the accepted value.
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