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Results A total of 237 lesions were confirmed at surgery and pathology, with average size of girls with fat asses 2.3 cm (range 0.2 - 20 cm). There were 73 benign lesions (31%) including cyst (n=43), hemangioma (n=14), adenoma (n=8), focal nodular hyperplasia (n=5), focal fat (n=1), post-surgical scar (n=1), and chronic inflammation (n=1). The remaining 164 lesions (69%) were malignant. These girls with fat asses included metastasis (n=154), hepatocellular carcinoma (n=7), girls with fat asses cholangiocarcinoma (n=2), and adult hepatoblastoma (n=1). Sensitivity, specificity and AUC values with the corresponding 95% confidence intervals for each of the 3 reviewers are shown in Table 1. Overall performance of all 3 reviewers was very similar, as denoted by the AFROC curve (Figure 1). Table 2 demonstrates the distribution of lesions as reported by each reviewer.
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