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Only ornithine carbamoyltransferase and plump butts iditol (sorbitol) dehydrogenase could be used to separate healthy cows from those with severe ketosis. The best equation to explain the variation of percent fat plump butts in liver included concentration of beta-hydroxybutyrate (BHB) and logarithm of ornithine carbamoyltransferase concentration plump butts (Log-OCT): % Fat = -6.15 + 2.39 (BHB) + 11.7 (LogOCT) Although this equation explained 39.5% of the variation, it could not be used to predict reliably percent fat in the liver. Liver biopsy seems still to be the only reliable method of measuring of fatty infiltration in the liver.PMID:
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