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The investigators in those studies found that once chronic alcohol ingestion and viral, pharmacologic, autoimmune, plump naked and metabolic causessuch as hemochromatosiswere ruled out, virtually all of the remaining patients proved to have NAFLD. 6. Do patients with NAFLD present with any classic symptoms? Most patients with NAFLD are plump naked asymptomatic. Abnormal liver function test results are usually the first sign plump naked of a disorder. Hepatomegaly may be present, but it is usually not detected on physical examination. Occasionally, ultrasound examination performed for other reasons will reveal an enlarged liver. 7. Is there a specific pattern of liver function abnormalities that is characteristic of NAFLD? The serum transaminase levels are usually not greatly elevated, but in contrast with alcoholic liver disease, the alanine aminotransferase (ALT) level will be higher than the aspartate aminotransferase (AST) level. The ferritin level may also be elevated, sometimes leading to a misdiagnosis of hemochromatosis.
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