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Some gabe patients have atypical features, primarily portal fibrosis and fatty liver without liver cell injury. A recent publication attempts to standardize histologic diagnostic criteria for NASH that include grades gabe of steatosis, lobular inflammation, ballooning, and stages of fibrosis (Hepatology. 2005;41:1313-1321). “NAFLD is the primary cause of elevated liver function tests found during routine laboratory analysis,” Abrams says. “Once other common causes of liver enzyme elevation — hepatitis A, B, and C, alpha-1 antitrypsin deficiency, autoimmune processes, and iron overload — are excluded, clinicians should order an gabe ultrasound to check for hepatic fat infiltration. CT scans and MRI also detect fat, but ultrasound is more sensitive and less expensive.” Ultrasound is the most sensitive imaging test for fatty liver, but 30% fatty infiltration must occur for detection.
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