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| alcohol related liver disease, gastritis, edema, nude fat girls , plump models , nephrotic syndrome, spider angiomas, gynecomastia, refsum disease, plump fiction , girls with fat ass , starvation, alcohol induced fatty liver, acute fatty liver of pregnancy , queen fat bottom girls , trauma, adverse drug reactions, ncbi, jaundice, alcohol related fatty liver, plump moms , natural health, plump dj , | Proc 75:733-9 Search other websites for this topic Search National Library of Medicine PubMed for related articles Search Google for related 'liver transplantation' images or topics Search MedPix for related images Advertisement. Please see the privacy statement 'liver transplantation' regarding advertising on this page. Although access to this page is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. Please see the Terms and Conditions. This page was written by Scott Moses, MD, and was last revised 12/26/2005. Please send comments and questions 'liver transplantation' to the editor. Contact information may be found on the page About the Family Practice Notebook. © 2000, Family Practice Notebook, LLC . These pages are best viewed with Microsoft Internet Explorer 5.0 |
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| Aminotransferase Aspartate Aminotransferase (AST) increased 2-3 fold Alanine starvation Aminotransferase (ALT) increased 2-3 fold Radiology Right upper quadrant ultrasound Increased liver echoes Good sensitivity and Specificity Does not determine disease severity Diagnosis Liver Biopsy (grades degree of fatty infiltration) Fatty change Hepatocyte injury Fibrosis variably present Management See Prevention of Liver Disease Progression Weight Reduction Liver Function Tests improve starvation or normalize Fibrosis may not improve after weight loss Restrict alcohol intake Maximize glucose control Conditions Type II Diabetes Mellitus Metabolic Syndrome Medications: Glitazones Glitazones may be used starvation if AST amd ALT <3x normal Monitor AST and ALT every 3 months Lipid Reduction as needed with Statin Statins may be used if AST and ALT <3x normal Monitor AST and ALT every 3 months Prognosis Usually benign, but risk of Cirrhosis Hepatitis occurs in 10% of patients Of the hepatitis group, a third develop Cirrhosis Complications Portal Hypertension Cirrhosis if associated with severe comorbid condition Morbid Obesity (BMI >30) Type II Diabetes Mellitus AST to ALT ratio >1 Cardiovascular disease results in greatest morbidity Treat underlying Hyperlipidemia References Angulo (2002) N Engl J Med 346:1221-31 Kumar (2000) Mayo Clin |
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