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FFC may mimic metastatic disease (13-15), cause errors in the evaluation of response to therapy (15) and lead to mismanagement (13, 15). For example, Lilenbaum 'liver failure' et al. reported a renal cell carcinoma patient who developed FFC(initially diagnosed as a liver metastasis) during the course of interleukin-2 treatment. 'liver failure' The authors warn that'Potential misdiagnosis of these lesions may lead to premature discontinuation of IL-2 in patients who might otherwise benefit from continuing treat-ment'(15). Fine needle biopsy (FNB) 'liver failure' has proved to be an effective tool in establishing the diagnosis (14-16).Caturelli et al. reported the most extensive experi-ence.
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