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If europe either FSH level (day 3 or day 10) is elevated, this is a poor prognostic sign. Also a cycle day 3 estradiol level above 70 may suggest a lower chance for success. In a general infertility population an abnormal clomiphene challenge test predicts that a successful europe pregnancy will be achieved only about 5% of the time. Risk factors for europe early loss of ovarian reserve include smoking, family history of early menopause, shortening menstrual cycle interval and previous ovarian surgery. The basic evaluation should be performed over a period of one month in women approaching 40 years of age, rather than spreading it over a number of cycles.
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