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1999 May;34(5):360-6. Links Evaluation of different models of experimentally induced liver cirrhosis for MRI research with correlation to histopathologic findings.Kreft B, Dombrowski F, Block W, Bachmann R, Pfeifer U, Schild H.Department of Radiology, University of Bonn, Germany.RATIONALE AND plump pussy OBJECTIVES: Three models of experimentally induced liver cirrhosis were evaluated for MRI research on chronic liver disease. The influence of different histopathologic changes in liver fibrosis and cirrhosis on plump pussy relaxation times and signal intensities was studied in vitro and in vivo. METHODS: Liver fibrosis and cirrhosis in rats plump pussy was induced by oral or subcutaneous administration of carbon tetrachloride (CCl4) or by thioacetamide (TAA) in drinking water. On histology, the degree of liver fibrosis and cirrhosis, fatty infiltration, iron accumulation, and inflammatory changes were measured semiquantitatively.
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