Macrovesicular steatosis (Image 1) simulations busty plump

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Macrovesicular steatosis (Image 1) is the rule; hepatocytes containing one or more large fat droplets displace the nucleus to an eccentric position. Occasional lipid release from rupture of distended hepatocytes may produce a mild localized inflammatory response (lipogranulomas) composed predominantly of macrophages and occasional lymphocytes. Although infiltration of liver with inflammatory cells is not prominent in patients with steatosis busty plump alone, in some instances, fibrosis around terminal venules (ie, perivenular fibrosis) and/or hepatocytes (ie, pericellular fibrosis) has been noted. busty plump Early changes observed with the electron microscope include accumulation of membrane-bound fat droplets, proliferation of smooth busty plump endoplasmic reticulum, and gradual distortion of mitochondria. Microvesicular steatosis also now is being recognized with increasing frequency. Alcoholic foamy degeneration (microvesicular fatty change) was the term used by Uchida et al (1983) to describe a clinical syndrome in people with chronic alcoholism.
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