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of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.OBJECTIVE: The purpose of the study was to develop quantitative and qualitative criteria for diagnosing fatty liver on contrast-enhanced helical CT. SUBJECTS AND METHODS: hereditary fructose intolerance Differential liver-spleen attenuation was evaluated between 80 and 120 sec after injection in 76 patients who underwent contrast-enhanced helical CT. Unenhanced CT images had earlier established fatty liver when the liver minus spleen attenuation difference was less than or equal to -10 H (n = 18). Four hereditary fructose intolerance observers who had not seen the unenhanced images used contrast-enhanced CT images to assess the presence of fatty liver hereditary fructose intolerance on a five-point Likert scale, the presence of geographic areas spared from fatty infiltration, and the relative liver-spleen attenuation.
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