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Animal research indicates that the metabolism boosting, appetite suppressing claims are probably true. Most studies show that ephedrine plus caffeine (or guarana) promotes greater weight loss than a placebo. There are side effects. Since 1993, the FDA estimates that there have been reports of 58 deaths and almost 400 adverse effects associated with ephedrine. The adverse effects include seizures, strokes, irregular heartbeat, protein bars heart attack, high blood pressure, nervousness, insomnia, and protein bars suicidal acts. These effects occur because ephedrine is a stimulant that can protein bars overstimulate the heart and nervous system. The FDA advises anyone with high blood pressure, heart conditions, diabetes or neurological disorders to avoid ephedrine. The expert take on ephedrine is that the bulk of research indicates that it helps people lose weight, but it's not necessarily safe.
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